A prerequisite for any person claiming to be a prosperous and successful in life is to be healthy and stay young. Today there are plenty of clinics and medical centers working in the field of rejuvenation and renewal period of active human longevity. However, to choose from the "sea" of such medical institutions one that is really best and safe is a very difficult task for a person not related to medicine. Nevertheless, after a long search and numerous consultations, we were advised to address a question "How to be healthy and stay young?" precisely to the Saint Petersburg Institute of Bioregulation and Gerontology, which is recognized today as a world leader in the field of prevention of age-related pathologies. We addressed that question to S. V. Trofimova, MD, Professor, and the Director General of the Tree of Life Clinic.

 Svetlana Vladislavovna,  how to enjoy good health and remain young? 

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It is hardly possible to deny that everybody is concerned about getting old.  A century ago, I.I. Mechnikov noted that  “among all disharmonies of the human nature, the main one lies in the incongruity between the brevity of life and the need to live much longer".  In  recent decades developed countries have focused on rejuvenation technologies, slowing the aging process and  extending the period of active human longevity. A great number of clinics and health centers, world-wide, have emphasized extensive research in this field. The most famous clinic and research centers dedicated to cellular, anti-aging therapy is Clinique La Prairie in Montreux (Switzerland). Being the oldest clinic working in this field, it has earned a well-deserved reputation among members of royal families, politicians and  celebrities, businessmen. CliniqueLaPrarie is famous for its CLP method – “Cell Revitalization”, using the extract from embryonic sheep liver cells. 

A new approach in the field of cell therapy, using modern technology, allows for the creation of a new class of peptide bioregulators, slowing down aging processes, based on the findings of extensive research  done at the St. Petersburg Institute of Bioregulation and Gerontology (SPb IBG). 

The method applied at the Clinic of Predictive Medicine "The tree of life” is based on the innovative scientific achievements of the St. Petersburg Institute of Bioregulation and Gerontology in improving the quality of health and the prevention of age-related pathologies. Unique anti-aging technologies are based on the application of peptide bioregulators, recognized at the XXth World Congress of Gerontology and Geriatrics (Korea, 2014) as scientifically proven geroprotectors. 
Svetlana Vladislavovna, you often use the word “gerontology”. What does it mean in this context?  Does it mean the science of old age? We are not interested in the aging process! We are still young and want  to remain so for as long as possible. I do not believe that we truly need gerontology! 
I would like to bring to your attention to the fact that the science of gerontology is not about old age, but t to the contrary, it is the science of maintaining youth and health. Unlike geriatrics, which deals with practical help to elderly individuals, gerontologists develop tools and technologies to slow down the aging processes and extend the human span of physical and mental activity. In Europe, this field is better known as anti-aging medicine. In addition, no matter how strange it may sound,  today  Russia is taking the leading position in the field of gerontology in thanks to the unique technologies and products created by scientists from the St. Petersburg Institute of Bioregulation and Gerontology. Long-term basic research in the field of gerontology allows for the creation of innovative medicines specifically, peptide geroprotectors. 
– When do people begin to physically age?  What are the visual signs that a person can identify as physical  aging? 
After 25 years old, a natural biological process of aging begins and we first see it in the skin. Skin is the first barrier of negative external environment on the way to the human organism. In addition, the skin is a complex organ that performs many functions. The skin protects the body from external influences (mechanical, chemical, physical), and it can elicit protective agent against various infectious diseases, it creates a reliable barrier to pathogens involved in the processes of respiration, allocation of thermoregulation and its role in the metabolism is high. After 25-30 years old, the skin begins to lose gradually moisture, elasticity by slowing down the process of collagen and elastin. Skin becomes drier, looks older; its immune function decreases and generates fewer young cells. Therefore, the natural protective barrier of the skin becomes un- reliable and  inhibits negative environmental impact. The appearance of wrinkles, decreased skin turgor, skin color deterioration becomes a warning signal to make an appointment for a consultation with a doctor specializing in the restoration  of our most powerful barrier against the elements–the skin. 
However, this is not the only sign of the incipient aging process. Changes in the speed and quality of various metabolic processes occurring in the body, is another indication of advanced aging and should not affect the overall well-being, including minor illnesses. A natural consequence of aging is the reduction of melatonin production (“youth hormone”) and shortening of telomeres lengths (DNA endings at the ends of chromosomes). Peptide bioregulators are able to activate their own production of melatonin and increase the length of telomeres, thus helping to slow the aging process by the “rejuvenation” of senescent cells. Entering the body, peptides literally “rejuvenate” itfrom the  inside, thus restoring their own protein synthesis in the cell. 
For early detection of accelerated aging signs, highly skilled professionals of the Clinic of Predictive Medicine perform comprehensive examinations of our patients’ health in order to assess their biological age and the rate of aging. 
It is a scientifically proven fact that the biological limit of human life span is increasing to 100-120 years. However, the average life expectancy currently ranges from 70-75 years, resulting in premature aging. Consequently, an individual now has a 30-40 years life reserve. Stresses, poor environmental factors , harmful radiation, unbalanced diet and lifestyle do not allow for the implementation of this biological reserve in the genetic program. However, since we all age differently: an individual's cardiovascular, nervous or endocrine system wears out faster. Each person has his / her own vulnerabilities. Therefore, the sooner a person performs a full examination of the organism with the assessment of health status and the rate of aging, the chances of save his / her health and youthfulness increases tremendously. 
We value time of our patients and understand their daily routine, that is why we schedule a comprehensive diagnostics of the whole body in 2.5 to 3.0 hours. It should be noted that applied diagnostic methods include unique molecular genetic analysis allowing for the assessment of  risks of various somatic (heart attack, stroke, Alzheimer's disease, diabetes, etc.) and ontological diseases in our patients. Molecular genetic testing, in the early pre symptomatic period, presents an opportunity to identify predisposition of diseases existing in the human genome, using unique and innovative technology developed by scientists of the St. Petersburg Institute of Bioregulation and Gerontology, enabling identification, early detention and  prevention. The results of a comprehensive survey allows for an individual selection of peptide geroprotectors complex, which includes the revealed pathology and genetic predisposition to disease. At our clinic wedeveloped a non-surgical treatment and prevention programs for identified diseases specifically for each patient based on peptide bioregulators. 
- How do peptide geroprotectors work? 
Peptide bioregulators or geroprotectors have a broad spectrum of biological activity. By activating gene expression, peptides stimulate protein synthesis in the body cells and regulate the functional activity of human organs and systems.  Impact of peptide bioregulators on DNA prevents chromosomal aberrations, providing genetic stability throughout life. Thus, the distinctive feature of bio control treatment is its physiological regulatory effect on metabolic processes in a cell that is known to be infringed in various diseases and in the aging process. Peptide bioregulators do not have side effects and do not cause allergic reactions, because they consist of natural amino acids, present in the norm in our organism. 
- What do you mean when you talk about innovative technologies to preserve youth and health?
Fiirst, these are certainly unique peptide geroprotectors, and second, this technique is for assessment of biological age and predisposition to disease, based on the results of the genetic analysis. Only the knowledge of the individual characteristics of the human organism, its biological age and rate of aging allows approaching to the problem of preserving the patient's health and youth from a biological standpoint. Long-term clinical studies have proven the unique capabilities of the peptides to slow the premature aging processes in the body. Through the diagnostic  results, our patients are provided with individually designed treatment and preventive programs for the prevention of age-related pathology, complications of diabetes, osteoporosis, arthritis, female urinary incontinence, treatment of macular degeneration, diabetic retinopathy, prostatitis, erectile dysfunction in men of any age and other diseases. Non-surgical techniques, used exclusively at the Clinic of Predictive Medicine "The Tree of Life”, allow for painless treatment of the patient without interruption of normal daily routines. For example, having a five-day treatment consisting of inhaled peptide immunomodulators, patients can effectively strengthen the immune system during the seasonal increase in the frequency of respiratory diseases. Complex programs such as “Detoxification” and “Revitalization” allow for strengthening and normalizing the functioning of the immune and antioxidant systems of the body, providing visible rejuvenating effects on the skin as well as the entire body. Peptide geroprotectors realize their effect on the skin and subcutaneous fat by stimulating regeneration of skin cells, improvement of blood circulation and micro circulation, increasing immunity factors, activation of lipolysis, including synthesis of collagen - elastin skeleton of skin. Visible effects are noted after the first procedures. Wraps with a unique set of peptide bioregulators, have a beneficial effect on the nervous system (providing an anti-stressful and relaxing effect), render an organism a cleansing, detoxification, restorative effect, and increase the body's immune defenses. For skin, it lifts, while improving the texture, color and moisture of the skin.
 
Innovative technologies for assessment of biological age, reserve possibilities of the human organism and its genetic predisposition to diseases enable professionals of Predictive Medical Center's The Tree of Life program, to identify the first signs of  disease and accelerated aging of the patient. Therefore, early diagnosis, combined with gene-regulating action of peptides, enables a targeted approach into treating diseases and the prevention of accelerated aging.
The use of peptide bioregulators is one of the major innovations in medicine and allows to substantially slow aging by restoring tissue regeneration, a powerful anti-tumor effect, and by increasing the cell resource of an organism.
 
Unfortunately, as a rule, the patient visits a doctor after the onset of an illness. However, one must always remember that to avoid illness is much easier and more cost effective than to cure it! 

Quality diagnostics, timely prevention and the use of innovative technologies are the three main components of the success of the Predictive Medical Center in maintaining the health and longevity of our patients!